To do this, click on the Tools menu from the button with three horizontal lines (or three vertical dots) in the upper right corner of the the Google Chrome browser, and then click on "Settings" from the drop down menu.
The Settings tab will indicate your current setting for your homepage (titled “On Startup”) and your default search provider (titled “Search”). If MySearch is currently set as your homepage or default search provider, you must disable the MySearch extension in order to change the setting. Chrome will display an option to disable the extension as shown below. You can click on the "Disable Extension" button and then set your desired homepage or search provider. In some cases, you may have separate MySearch extensions installed for your homepage and default search provider settings, and you may need to disable them separately. (MySearch extensions are GameOn, MuzikFury and SeenOnScreen.)
If you want to remove the MySearch New Tab page, please follow these instructions on how to remove the extension from Chrome.